EXPERIMENTAL EVALUATION OF A MODEL FOR THE ORIGIN OF THE THIRD HEART SOUND.

Research output: Contribution to conferencePaperpeer-review

Abstract

A model is presented that incorporates the basic diastolic properties of the heart and supports the hypothesis of a muscular origin. The model is evaluated by comparing it with data obtained previously from human subjects with cardiomyopathy and with an experimental canine model. For the human data, model parameters are adjusted by matching the in vivo indices of measured diastolic function to those of the model. For the canine data, the model parameters are determined by progressive volume expansion. The ventricular pressure and volume are recorded continuously to measure active and passive cardiac function. The results indicate that stress relaxation due to the viscoelastic properties of the cardiac muscle are primarily responsible for a more sudden rapid filling wave.

Original languageEnglish (US)
Pages333-335
Number of pages3
StatePublished - 1987

All Science Journal Classification (ASJC) codes

  • Bioengineering

Fingerprint

Dive into the research topics of 'EXPERIMENTAL EVALUATION OF A MODEL FOR THE ORIGIN OF THE THIRD HEART SOUND.'. Together they form a unique fingerprint.

Cite this