Expression of c-fos protein in lumbosacral spinal cord in response to vaginocervical stimulation in rats

Sandra Chinapen; Jennifer M. Swann; Judith L. Steinman; Barry Komisaruk

doi:10.1016/0304-3940(92)90211-O

Expression of c-fos protein in lumbosacral spinal cord in response to vaginocervical stimulation in rats

Sandra Chinapen, Jennifer M. Swann, Judith L. Steinman, Barry Komisaruk

Rutgers Newark, Psychology

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

The pattern of vaginocervical stimulation-evoked expression of the proto-oncogene c-fos in lumbar 5-sacral 1 segments of the spinal cord of ovariectomized adult rats was mapped using immunocytochemistry. A calibrated force of mechanostimulation was applied to the vaginal cervix of experimental animals and to the perineum of control animals while they were gently restrained. The number of cells expressing c-fos was significant greater in the experimental than the control animals in laminae I, IV, V-VI and X. The implications of the present findings for elucidating the spinal pathways mediating the various behavioral, neuroendocrine and autonomic effects of vaginocervical stimulation (VS) are discussed.

Original language	English (US)
Pages (from-to)	93-96
Number of pages	4
Journal	Neuroscience Letters
Volume	145
Issue number	1
DOIs	https://doi.org/10.1016/0304-3940(92)90211-O
State	Published - Sep 28 1992

All Science Journal Classification (ASJC) codes

Neuroscience(all)

Access to Document

10.1016/0304-3940(92)90211-O

Fingerprint Dive into the research topics of 'Expression of c-fos protein in lumbosacral spinal cord in response to vaginocervical stimulation in rats'. Together they form a unique fingerprint.

Cite this

@article{20790f675ce94f84859c73905f8cb282,

title = "Expression of c-fos protein in lumbosacral spinal cord in response to vaginocervical stimulation in rats",

abstract = "The pattern of vaginocervical stimulation-evoked expression of the proto-oncogene c-fos in lumbar 5-sacral 1 segments of the spinal cord of ovariectomized adult rats was mapped using immunocytochemistry. A calibrated force of mechanostimulation was applied to the vaginal cervix of experimental animals and to the perineum of control animals while they were gently restrained. The number of cells expressing c-fos was significant greater in the experimental than the control animals in laminae I, IV, V-VI and X. The implications of the present findings for elucidating the spinal pathways mediating the various behavioral, neuroendocrine and autonomic effects of vaginocervical stimulation (VS) are discussed.",

author = "Sandra Chinapen and Swann, {Jennifer M.} and Steinman, {Judith L.} and Barry Komisaruk",

year = "1992",

month = sep,

day = "28",

doi = "10.1016/0304-3940(92)90211-O",

language = "English (US)",

volume = "145",

pages = "93--96",

journal = "Neuroscience Letters",

issn = "0304-3940",

publisher = "Elsevier Ireland Ltd",

number = "1",

}

TY - JOUR

T1 - Expression of c-fos protein in lumbosacral spinal cord in response to vaginocervical stimulation in rats

AU - Chinapen, Sandra

AU - Swann, Jennifer M.

AU - Steinman, Judith L.

AU - Komisaruk, Barry

PY - 1992/9/28

Y1 - 1992/9/28

N2 - The pattern of vaginocervical stimulation-evoked expression of the proto-oncogene c-fos in lumbar 5-sacral 1 segments of the spinal cord of ovariectomized adult rats was mapped using immunocytochemistry. A calibrated force of mechanostimulation was applied to the vaginal cervix of experimental animals and to the perineum of control animals while they were gently restrained. The number of cells expressing c-fos was significant greater in the experimental than the control animals in laminae I, IV, V-VI and X. The implications of the present findings for elucidating the spinal pathways mediating the various behavioral, neuroendocrine and autonomic effects of vaginocervical stimulation (VS) are discussed.

AB - The pattern of vaginocervical stimulation-evoked expression of the proto-oncogene c-fos in lumbar 5-sacral 1 segments of the spinal cord of ovariectomized adult rats was mapped using immunocytochemistry. A calibrated force of mechanostimulation was applied to the vaginal cervix of experimental animals and to the perineum of control animals while they were gently restrained. The number of cells expressing c-fos was significant greater in the experimental than the control animals in laminae I, IV, V-VI and X. The implications of the present findings for elucidating the spinal pathways mediating the various behavioral, neuroendocrine and autonomic effects of vaginocervical stimulation (VS) are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0026714525&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026714525&partnerID=8YFLogxK

U2 - 10.1016/0304-3940(92)90211-O

DO - 10.1016/0304-3940(92)90211-O

M3 - Article

C2 - 1461575

AN - SCOPUS:0026714525

VL - 145

SP - 93

EP - 96

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 1

ER -