Extrapulmonary tuberculosis presenting as a cavernous sinus syndrome: Case report with review of existing literature

Shashi Kapadia, Amee Patrawalla

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Tuberculoma involving the cavernous sinus is a rare presentation of CNS disease, with only twelve cases reported in previous literature. We report a case of a 48 year old woman who presented with a right cavernous sinus syndrome of 2 months duration. MRI showed a mass in the right cavernous sinus, and serologic workup revealed an elevated sedimentation rate and positive Quantiferon®-GOLD testing. 18-FDG PET-CT demonstrated a hypermetabolic 3cm subcarinal lymph node, and lymph node biopsy showed caseating granuloma. Culture of lymphatic tissue grew drug-sensitive M. tuberculosis. The patient was treated with a non-standard 4-drug regimen and prednisone, with rapid improvement of symptoms and radiologic abnormalities. Total length of treatment was 12 months. In addition, we review the 12 cases found in literature, and discuss clinical features, diagnostic dilemmas, and approaches to treatment.

Original languageEnglish (US)
Pages (from-to)97-100
Number of pages4
JournalIDCases
Volume1
Issue number4
DOIs
StatePublished - 2014

All Science Journal Classification (ASJC) codes

  • Infectious Diseases

Keywords

  • CNS tuberculosis
  • Cavernous sinus syndrome
  • Extrapulmonary tuberculosis
  • FDG-PET
  • Tuberculoma
  • Tuberculosis

Fingerprint Dive into the research topics of 'Extrapulmonary tuberculosis presenting as a cavernous sinus syndrome: Case report with review of existing literature'. Together they form a unique fingerprint.

Cite this