F-18 FDG positron emission tomography demonstrates resolution of non-Hodgkin's lymphoma of the parotid gland in a patient with Sjogren's syndrome before and after anti-CD20 antibody rituximab therapy

Wei Jen Shih, Nasrin Ghesani, Zhuang Hongming, Abass Alavi, Steven Schusper, Davis Mozley

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Salivary gland non-Hogdgkin's lymphoma (NHL) in patients with Sjogren's syndrome frequently develops from rheumatoid factor B cells. The authors describe a patient with NHL of the parotid glands associated with Sjogren's syndrome whose initial positron emission tomographic (PET) findings included abnormal F-18 fluorodeoxyglucose (FDG) uptake in the parotid glands. After rituximab therapy, a follow-up PET study confirmed a positive response to treatment. This illustrates that F-18 FDG PET can be used to monitor the therapeutic response of NHL parotid glands associated with Sjogren's syndrome.

Original languageEnglish (US)
Pages (from-to)142-143
Number of pages2
JournalClinical nuclear medicine
Volume27
Issue number2
DOIs
StatePublished - 2002

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Keywords

  • Fluorine-18 Fluorodeoxyglucose
  • Monoclonal Antibody Therapy
  • Non-Hodgkin's Lymphoma
  • Rituximab
  • Sjogren's Syndrome

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