Familial risk factors in autism

Michael Brimacombe, Ming Xue, Amisha Parikh

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Familial history risk factors in relation to autism were examined in a cohort of 164 autistic children referred to The Autism Center at New Jersey Medical School-University of Medicine and Dentistry of New Jersey, Newark, over a 2-year period (2001-2003). Information related to familial history was obtained from each family and reviewed by a clinician. It is shown that these families carry a higher overall burden of psychiatric and developmental illnesses compared to reported national levels. These families also carry a relatively high incidence of medical disorders, independently of developmental and psychiatric disorders. This work supports the underlying presence of genetic factors in the etiology of autism.

Original languageEnglish (US)
Pages (from-to)593-597
Number of pages5
JournalJournal of Child Neurology
Volume22
Issue number5
DOIs
StatePublished - May 2007

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Keywords

  • Autism
  • Developmental disorders
  • Epidemiology
  • Family history
  • Psychiatric disorders

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