Favre−Racouchot disease: protective effect of solar elastosis

Christopher Yeh, Robert A. Schwartz

Research output: Contribution to journalReview articlepeer-review

Abstract

Favre−Racouchot disease (FRD) is an occupational disorder characterized by solar elastosis with open and cystically dilated comedones that tend to appear on the periorbital and temporal face of elderly light-complexioned men. It is a benign condition caused by chronic excessive ultraviolet exposure, as well as ionizing radiation and/or smoking. However, malignant skin neoplasms are uncommonly observed arising in FRD, which suggests a protective role of some element of FRD against carcinogenesis. We explore elastosis as a possibly beneficial tissue response. The clinical manifestations, pathogenesis, and recommended treatment options of this disorder are reviewed.

Original languageEnglish (US)
Pages (from-to)217-222
Number of pages6
JournalArchives of Dermatological Research
Volume314
Issue number3
DOIs
StatePublished - Apr 2022

All Science Journal Classification (ASJC) codes

  • Dermatology

Keywords

  • Carcinogenesis
  • Comedones
  • Cysts
  • Favre−Racouchot disease
  • Nodules
  • Photoaging
  • Solar elastosis

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