Folate and anti-folate transport in mammalian cells.

B. A. Kamen, Joseph Bertino

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

The transport of folate by murine leukemia cells, hepatic cells, choroid plexus and intestine is a complicated process involving at least two different carrier-mediated processes and/or passive diffusion by certain cells. Although there are marked similarities between many of the models studied, there are also striking differences, especially with regards to specificity of the transport system. This review compares and contrasts these different systems as well as briefly examining the role of folate binders and newer techniques for studying folate and anti-folate delivery to cells.

Original languageEnglish (US)
Pages (from-to)62-67
Number of pages6
JournalAntibiotics and chemotherapy
Volume28
StatePublished - Jan 1 1980
Externally publishedYes

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Folic Acid
Choroid Plexus
Intestines
Hepatocytes
Leukemia

All Science Journal Classification (ASJC) codes

  • Pharmacology

Cite this

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title = "Folate and anti-folate transport in mammalian cells.",
abstract = "The transport of folate by murine leukemia cells, hepatic cells, choroid plexus and intestine is a complicated process involving at least two different carrier-mediated processes and/or passive diffusion by certain cells. Although there are marked similarities between many of the models studied, there are also striking differences, especially with regards to specificity of the transport system. This review compares and contrasts these different systems as well as briefly examining the role of folate binders and newer techniques for studying folate and anti-folate delivery to cells.",
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Folate and anti-folate transport in mammalian cells. / Kamen, B. A.; Bertino, Joseph.

In: Antibiotics and chemotherapy, Vol. 28, 01.01.1980, p. 62-67.

Research output: Contribution to journalReview article

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AU - Kamen, B. A.

AU - Bertino, Joseph

PY - 1980/1/1

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N2 - The transport of folate by murine leukemia cells, hepatic cells, choroid plexus and intestine is a complicated process involving at least two different carrier-mediated processes and/or passive diffusion by certain cells. Although there are marked similarities between many of the models studied, there are also striking differences, especially with regards to specificity of the transport system. This review compares and contrasts these different systems as well as briefly examining the role of folate binders and newer techniques for studying folate and anti-folate delivery to cells.

AB - The transport of folate by murine leukemia cells, hepatic cells, choroid plexus and intestine is a complicated process involving at least two different carrier-mediated processes and/or passive diffusion by certain cells. Although there are marked similarities between many of the models studied, there are also striking differences, especially with regards to specificity of the transport system. This review compares and contrasts these different systems as well as briefly examining the role of folate binders and newer techniques for studying folate and anti-folate delivery to cells.

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VL - 28

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JO - Antibiotics and chemotherapy

JF - Antibiotics and chemotherapy

SN - 0066-4758

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