From frontotemporal lobar degeneration pathology to frontotemporal lobar degeneration biomarkers

Chadwick M. Hales, William T. Hu

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Frontotemporal dementia (FTD) is an increasingly recognized cause of dementia. This review discusses the different FTD clinical syndromes and frontotemporal lobar degeneration (FTLD) pathological correlates as well as new genetic and proteomic findings that have added to our understanding of FTLD pathogenesis. Various diagnostic modalities including the use of biomarkers will also be addressed. Finally we will highlight future directions in the FTD field. More research is needed to elucidate the cellular mechanisms of neurodegeneration in FTLD and improve clinical diagnostic capabilities.

Original languageEnglish (US)
Pages (from-to)210-220
Number of pages11
JournalInternational Review of Psychiatry
Volume25
Issue number2
DOIs
StatePublished - Apr 2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

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