Until October 2008, coronary drug-eluting stents with a diameter of ≤2.5 mm were not approved by the FDA. Target vessels of ≤2 mm in diameter pose a major challenge in view of high restenosis rates when stented bare metal stents (BMS) are used and distal edge dissection when oversized stents are deployed. Described is a method ("funneling") to optimize stenting of small vessels. This strategy combines stenting the distal part of the lesion with short (8-12 mm length) 2-mm bare metal stent while stenting with a larger-diameter (≥2.5 mm) drug-eluting stent (DES) with considerable DES-BMS overlap (leaving only the distal 4-6 mm of the BMS not overlapped by a DES). The two stents create a funnel that is for the most part drug eluting. With funneling, both drug elution and larger diameter are attained, minimizing both edge dissection and restenosis.
All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine
- Drug eluting stents