Future Approaches and Therapeutic Modalities for Acute Liver Failure

Pavan Patel; Nneoma Okoronkwo; Nikolaos T. Pyrsopoulos

doi:10.1016/j.cld.2018.01.011

Future Approaches and Therapeutic Modalities for Acute Liver Failure

Pavan Patel, Nneoma Okoronkwo, Nikolaos T. Pyrsopoulos

New Jersey Medical School (NJMS), Medicine, Division of Gastroenterology

Research output: Contribution to journal › Review article › peer-review

21 Scopus citations

Abstract

The current gold standard for the management of acute liver failure is liver transplantation. However, because of organ shortages, other modalities of therapy are necessary as a possible bridge. This article discusses the current modalities as well as the future management of acute liver failure. Liver assist devices, hepatocyte transplantation, stem cell transplant, organogenesis, and repopulation of decellularized organs are discussed.

Original language	English (US)
Pages (from-to)	419-427
Number of pages	9
Journal	Clinics in Liver Disease
Volume	22
Issue number	2
DOIs	https://doi.org/10.1016/j.cld.2018.01.011
State	Published - May 2018

All Science Journal Classification (ASJC) codes

Hepatology

Keywords

Acute liver failure
ELAD
HepatAssist
Hepatocyte transplant
Liver assist device
MARS
Organogenesis
Stem cell transplant

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10.1016/j.cld.2018.01.011

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title = "Future Approaches and Therapeutic Modalities for Acute Liver Failure",

abstract = "The current gold standard for the management of acute liver failure is liver transplantation. However, because of organ shortages, other modalities of therapy are necessary as a possible bridge. This article discusses the current modalities as well as the future management of acute liver failure. Liver assist devices, hepatocyte transplantation, stem cell transplant, organogenesis, and repopulation of decellularized organs are discussed.",

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AU - Okoronkwo, Nneoma

AU - Pyrsopoulos, Nikolaos T.

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AB - The current gold standard for the management of acute liver failure is liver transplantation. However, because of organ shortages, other modalities of therapy are necessary as a possible bridge. This article discusses the current modalities as well as the future management of acute liver failure. Liver assist devices, hepatocyte transplantation, stem cell transplant, organogenesis, and repopulation of decellularized organs are discussed.

KW - Acute liver failure

KW - ELAD

KW - HepatAssist

KW - Hepatocyte transplant

KW - Liver assist device

KW - MARS

KW - Organogenesis

KW - Stem cell transplant

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Future Approaches and Therapeutic Modalities for Acute Liver Failure

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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