Galactose biosensors using composite polymers to prevent interferences

Paul W. Stoecker, Alexander M. Yacynych, Paul Manowitz

Research output: Contribution to journalConference article

1 Scopus citations

Abstract

The development of biosensor that could detect low concentrations of galactose in human plasma is described. The objective required the development of an improved polymer coating to eliminate the effects of interferences at low current ranges. The use of a composite polymer to improve the protection of electrodes from electroactive interferences such as ascorbate, urate, and acetominophen, is demonstrated. The composite polymer consist of a non-conducting polymer of diaminobenzene and resorcinol and an anionic polymer of Nafion. The inclusion of the composite polymers facilitated the development of a sensitive galactose biosensor. The biosensor have a linear range from 50 microM to 6.0 mM, and a storage stability of one month. The biosensors demonstrated excellent recovery of plasma galactose.

Original languageEnglish (US)
Pages (from-to)509-510
Number of pages2
JournalPolymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering
Volume76
Publication statusPublished - Jan 1 1997
Externally publishedYes
EventProceedings of the 1997 Spring ACS Meeting - San Francisco, CA, USA
Duration: Apr 13 1997Apr 17 1997

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All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Polymers and Plastics

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