Garcinol from garcinia indica: Chemistry and health beneficial effects

Wenping Tang, Min Hsiung Pan, Shengmin Sang, Shiming Li, Chi Tang Ho

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Scopus citations

Abstract

Garcinol, a polyisoprenylated benzophenone, is isolated from fruit rinds of Garcinia indica, which has been used as an ornament, food ingredient as well as traditional medicine for centuries. With its unusual chemical structure, garcinol has generated considerable research interests in recent years because of its remedial qualities against many human diseases and ailments, mostly attributed to its potent antioxidant capabilities. There are increasing scientific evidences which demonstrate the anti-Tumorigenic effectiveness of garcinol, and apoptosis is the commonly suggested pathway. Garcinol has been found to modulate several cell signaling pathways involved in apoptosis and cancer development. The present review summarizes the current knowledge on the various biological activities of garcinol, focusing on its anti-Tumorigenic effects, as well as the chemistry aspects of this potential chemopreventive agent.

Original languageEnglish (US)
Title of host publicationTropical and Subtropical Fruits
Subtitle of host publicationFlavors, Color, and Health Benefits
PublisherAmerican Chemical Society
Pages133-145
Number of pages13
ISBN (Print)9780841228931
DOIs
StatePublished - May 14 2013

Publication series

NameACS Symposium Series
Volume1129
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Chemical Engineering

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