Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery

Prasad Subramaniam, Seung Jae Lee, Shreyas Shah, Sahishnu Patel, Valentin Starovoytov, Ki Bum Lee

Research output: Contribution to journalArticle

63 Scopus citations

Abstract

The development of non-toxic quantum dots and further investigation of their composition-dependent cytotoxicity in a high-throughput manner have been critical challenges for biomedical imaging and gene delivery. Herein, we report a rapid sonochemical synthetic methodology for generating a library of highly biocompatible ZnS-AgInS2 (ZAIS) quantum dots for cellular imaging and siRNA delivery.

Original languageEnglish (US)
Pages (from-to)4014-4019
Number of pages6
JournalAdvanced Materials
Volume24
Issue number29
DOIs
StatePublished - Aug 2 2012

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Keywords

  • nanomaterial libraries
  • non-toxic quantum dots
  • siRNA delivery
  • sonochemistry
  • stem cell imaging

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