Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery

Prasad Subramaniam, Seung Jae Lee, Shreyas Shah, Sahishnu Patel, Valentin Starovoytov, Ki Lee

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

The development of non-toxic quantum dots and further investigation of their composition-dependent cytotoxicity in a high-throughput manner have been critical challenges for biomedical imaging and gene delivery. Herein, we report a rapid sonochemical synthetic methodology for generating a library of highly biocompatible ZnS-AgInS2 (ZAIS) quantum dots for cellular imaging and siRNA delivery.

Original languageEnglish (US)
Pages (from-to)4014-4019
Number of pages6
JournalAdvanced Materials
Volume24
Issue number29
DOIs
StatePublished - Aug 2 2012

Fingerprint

Small Interfering RNA
Semiconductor quantum dots
Imaging techniques
Cytotoxicity
Genes
Throughput
Chemical analysis

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Keywords

  • nanomaterial libraries
  • non-toxic quantum dots
  • siRNA delivery
  • sonochemistry
  • stem cell imaging

Cite this

Subramaniam, Prasad ; Lee, Seung Jae ; Shah, Shreyas ; Patel, Sahishnu ; Starovoytov, Valentin ; Lee, Ki. / Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery. In: Advanced Materials. 2012 ; Vol. 24, No. 29. pp. 4014-4019.
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Subramaniam, P, Lee, SJ, Shah, S, Patel, S, Starovoytov, V & Lee, K 2012, 'Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery', Advanced Materials, vol. 24, no. 29, pp. 4014-4019. https://doi.org/10.1002/adma.201201019

Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery. / Subramaniam, Prasad; Lee, Seung Jae; Shah, Shreyas; Patel, Sahishnu; Starovoytov, Valentin; Lee, Ki.

In: Advanced Materials, Vol. 24, No. 29, 02.08.2012, p. 4014-4019.

Research output: Contribution to journalArticle

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