Generation of Induced Pluripotent Stem Cells from Adult Rhesus Monkey Fibroblasts

Haisong Liu, Fangfang Zhu, Jun Yong, Pengbo Zhang, Pingping Hou, Honggang Li, Wei Jiang, Jun Cai, Meng Liu, Kai Cui, Xiuxia Qu, Tingting Xiang, Danyu Lu, Xiaochun Chi, Ge Gao, Weizhi Ji, Mingxiao Ding, Hongkui Deng

Research output: Contribution to journalLetterpeer-review

411 Scopus citations

Abstract

Induced pluripotent stem (iPS) cells can be generated from somatic cells by transduction with several transcription factors in mouse and human. However, direct reprogramming in other species has not been reported. Here, we generated monkey iPS cells by retrovirus-mediated introduction of monkey transcription factors OCT4, SOX2, KLF4, and c-MYC.

Original languageEnglish (US)
Pages (from-to)587-590
Number of pages4
JournalCell Stem Cell
Volume3
Issue number6
DOIs
StatePublished - Dec 4 2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Genetics
  • Cell Biology

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