Summary. The polymerase chain reaction makes it possible to analyse DNA sequences in a single cell and has led to a new approach for constructing genetic maps. We describe a procedure called ‘sperm typing’ which can accurately classify individual meiotic products as recombinant or non‐recombinant. This permits the linkage relationships among DNA polymorphisms to be determined without pedigree analysis.
|Original language||English (US)|
|Number of pages||11|
|State||Published - Jan 1 1991|
All Science Journal Classification (ASJC) codes
- Animal Science and Zoology
- genetic mapping
- sperm typing