Giant cell myocarditis after mitral valve replacement: Case report and studies of the nature of giant cells

Arnold B. Rabson; Frederick J. Schoen; Michael J. Warhol; Gilbert H. Mudge; John J. Collins

doi:10.1016/S0046-8177(84)80013-1

Giant cell myocarditis after mitral valve replacement: Case report and studies of the nature of giant cells

Arnold B. Rabson
, Frederick J. Schoen
, Michael J. Warhol
, Gilbert H. Mudge
, John J. Collins

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

A 22-year-old man with Marfan's syndrome and a history of antinuclear antibody-positive hepatitis died 25 days after undergoing cardiac valve replacement surgery for mitral valve prolapse. Giant cell myocarditis was found at autopsy. The multinucleated giant cells were shown by immunoperoxidase techniques to contain lysozyme, but not myosin or creatine phosphokinase suggesting that they were derived from macrophage, rather than myocyte, precursors.

Original language	English (US)
Pages (from-to)	585-587
Number of pages	3
Journal	Human Pathology
Volume	15
Issue number	6
DOIs	https://doi.org/10.1016/S0046-8177(84)80013-1
State	Published - Jun 1984
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pathology and Forensic Medicine

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10.1016/S0046-8177(84)80013-1

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abstract = "A 22-year-old man with Marfan's syndrome and a history of antinuclear antibody-positive hepatitis died 25 days after undergoing cardiac valve replacement surgery for mitral valve prolapse. Giant cell myocarditis was found at autopsy. The multinucleated giant cells were shown by immunoperoxidase techniques to contain lysozyme, but not myosin or creatine phosphokinase suggesting that they were derived from macrophage, rather than myocyte, precursors.",

author = "Rabson, \{Arnold B.\} and Schoen, \{Frederick J.\} and Warhol, \{Michael J.\} and Mudge, \{Gilbert H.\} and Collins, \{John J.\}",

year = "1984",

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T2 - Case report and studies of the nature of giant cells

AU - Rabson, Arnold B.

AU - Schoen, Frederick J.

AU - Warhol, Michael J.

AU - Mudge, Gilbert H.

AU - Collins, John J.

PY - 1984/6

Y1 - 1984/6

N2 - A 22-year-old man with Marfan's syndrome and a history of antinuclear antibody-positive hepatitis died 25 days after undergoing cardiac valve replacement surgery for mitral valve prolapse. Giant cell myocarditis was found at autopsy. The multinucleated giant cells were shown by immunoperoxidase techniques to contain lysozyme, but not myosin or creatine phosphokinase suggesting that they were derived from macrophage, rather than myocyte, precursors.

AB - A 22-year-old man with Marfan's syndrome and a history of antinuclear antibody-positive hepatitis died 25 days after undergoing cardiac valve replacement surgery for mitral valve prolapse. Giant cell myocarditis was found at autopsy. The multinucleated giant cells were shown by immunoperoxidase techniques to contain lysozyme, but not myosin or creatine phosphokinase suggesting that they were derived from macrophage, rather than myocyte, precursors.

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U2 - 10.1016/S0046-8177(84)80013-1

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ER -

Giant cell myocarditis after mitral valve replacement: Case report and studies of the nature of giant cells

Abstract

All Science Journal Classification (ASJC) codes

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