Ginsenoside Re: Pharmacological Effects on Cardiovascular System

Lu Peng, Shi Sun, Lai Hua Xie, Sheila M. Wicks, Jing Tian Xie

Research output: Contribution to journalReview article

49 Scopus citations

Abstract

Ginsenosides are the bioactive constituents of ginseng, a key herb in traditional Chinese medicine. As a single component of ginseng, ginsenoside Re (G-Re) belongs to the panaxatriol group. Many reports demonstrated that G-Re possesses the multifaceted beneficial pharmacological effects on cardiovascular system. G-Re has negative effect on cardiac contractility and autorhythmicity. It causes alternations in cardiac electrophysiological properties, which may account for its antiarrhythmic effect. In addition, G-Re also exerts antiischemic effect and induces angiogenic regeneration. In this review, we first outline the chemistry and the pharmacological effects of G-Re on the cardiovascular system.

Original languageEnglish (US)
Pages (from-to)e183-e188
JournalCardiovascular Therapeutics
Volume30
Issue number4
DOIs
StatePublished - Aug 1 2012

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

Keywords

  • Cardiovascular system
  • Chemistry
  • Electrophysiology
  • Ginseng
  • Ginsenoside Re
  • Pharmacological effect

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