Glucose intolerance and nine-year mortality in Japanese men in Hawaii

Katsuhiko Yano, Abraham Kagan, Daniel McGee, George G. Rhoads

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

The relationship between glucose intolerance and nine-year mortality was examined in a cohort of approximately 8,000 men of Japanese ancestry living in Hawaii who were 45 to 68 years of age at baseline examination. Age-adjusted mortality for death from all causes, cardiovascular disease, coronary heart disease and causes other than cardiovascular disease and cancer were significantly higher in men with glucose intolerance, defined by either medication for diabetes or 1-hour post-load serum glucose levels above the 90th percentile cut-point (225 mg/dl) at baseline examination, than in normoglycemic men. Although many cardiovascular risk factors were found to be associated with glucose intolerance, both post-load serum glucose level and medication for diabetes remained significant as risk factors for overall, cardiovascular and coronary death in multivariate logistic analysis in which confounding effects of age, blood pressure, serum cholesterol, body mass index and other important risk factors were taken into account.

Original languageEnglish (US)
Pages (from-to)71-80
Number of pages10
JournalThe American Journal of Medicine
Volume72
Issue number1
DOIs
StatePublished - Jan 1 1982
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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