Gut propulsion in mice infected with Trichinella spiralis

Michael Sukhdeo, N. A. Croll

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Previous investigators have shown that Trichinella spiralis increases intestinal motility and propulsion. We report here that primary infection with T. spiralis in the mouse increased gut propulsion, measured by the movement of nonabsorbable chromatography beads, on day 5 after infection but not 9 days after infection. Both cortisone acetate, an anti-inflammatory agent, and Lomotil, which reduces gut motility, could suppress the increase in gut propulsion seen 5 days after infection. The results suggest that early inflammation influences peristaltic activity and propulsion of intestinal contents.

Original languageEnglish (US)
Pages (from-to)906-910
Number of pages5
JournalJournal of Parasitology
Volume67
Issue number6
DOIs
StatePublished - Jan 1 1981
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Parasitology
  • Ecology, Evolution, Behavior and Systematics

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