Head and Neck Cancer in World Trade Center Responders: A Case Series

Judith M. Graber; Connie T. Chuang; Carolyn L. Ward; Kathleen Black; Iris G. Udasin

doi:10.1097/JOM.0000000000001386

Head and Neck Cancer in World Trade Center Responders: A Case Series

Judith M. Graber, Connie T. Chuang, Carolyn L. Ward, Kathleen Black, Iris G. Udasin

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

OBJECTIVE: The aim of this study was to report on cases of head and neck cancer (HNC) among World Trade Center (WTC) responders participating in the WTC Health Program and seen at Rutgers WTC Center of Clinical Excellence. METHODS: Medical records were abstracted by two clinical reviewers and discrepancies resolved. Cases were defined as WTC responders diagnosed with HNC between December 9, 2005, and December 31, 2016. RESULTS: Sixteen HNC patients met the case definition, most (13) arrived at the WTC location on 9/11 or within the following 2 days, and half worked in law enforcement during the 9/1 response. CONCLUSION: An association between HNC and WTC exposure is biologically plausible and should be further investigated. Research to enumerate the risk factor profile for these cancers may contribute to understanding mechanisms by which WTC exposure can contribute to carcinogenesis and to prevention and early detection strategies.

Original language	English (US)
Pages (from-to)	e439-e444
Journal	Journal of occupational and environmental medicine
Volume	60
Issue number	9
DOIs	https://doi.org/10.1097/JOM.0000000000001386
State	Published - Sep 1 2018

All Science Journal Classification (ASJC) codes

Public Health, Environmental and Occupational Health

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10.1097/JOM.0000000000001386

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title = "Head and Neck Cancer in World Trade Center Responders: A Case Series",

abstract = "OBJECTIVE: The aim of this study was to report on cases of head and neck cancer (HNC) among World Trade Center (WTC) responders participating in the WTC Health Program and seen at Rutgers WTC Center of Clinical Excellence. METHODS: Medical records were abstracted by two clinical reviewers and discrepancies resolved. Cases were defined as WTC responders diagnosed with HNC between December 9, 2005, and December 31, 2016. RESULTS: Sixteen HNC patients met the case definition, most (13) arrived at the WTC location on 9/11 or within the following 2 days, and half worked in law enforcement during the 9/1 response. CONCLUSION: An association between HNC and WTC exposure is biologically plausible and should be further investigated. Research to enumerate the risk factor profile for these cancers may contribute to understanding mechanisms by which WTC exposure can contribute to carcinogenesis and to prevention and early detection strategies.",

author = "Graber, {Judith M.} and Chuang, {Connie T.} and Ward, {Carolyn L.} and Kathleen Black and Udasin, {Iris G.}",

year = "2018",

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doi = "10.1097/JOM.0000000000001386",

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T1 - Head and Neck Cancer in World Trade Center Responders

T2 - A Case Series

AU - Graber, Judith M.

AU - Chuang, Connie T.

AU - Ward, Carolyn L.

AU - Black, Kathleen

AU - Udasin, Iris G.

PY - 2018/9/1

Y1 - 2018/9/1

N2 - OBJECTIVE: The aim of this study was to report on cases of head and neck cancer (HNC) among World Trade Center (WTC) responders participating in the WTC Health Program and seen at Rutgers WTC Center of Clinical Excellence. METHODS: Medical records were abstracted by two clinical reviewers and discrepancies resolved. Cases were defined as WTC responders diagnosed with HNC between December 9, 2005, and December 31, 2016. RESULTS: Sixteen HNC patients met the case definition, most (13) arrived at the WTC location on 9/11 or within the following 2 days, and half worked in law enforcement during the 9/1 response. CONCLUSION: An association between HNC and WTC exposure is biologically plausible and should be further investigated. Research to enumerate the risk factor profile for these cancers may contribute to understanding mechanisms by which WTC exposure can contribute to carcinogenesis and to prevention and early detection strategies.

AB - OBJECTIVE: The aim of this study was to report on cases of head and neck cancer (HNC) among World Trade Center (WTC) responders participating in the WTC Health Program and seen at Rutgers WTC Center of Clinical Excellence. METHODS: Medical records were abstracted by two clinical reviewers and discrepancies resolved. Cases were defined as WTC responders diagnosed with HNC between December 9, 2005, and December 31, 2016. RESULTS: Sixteen HNC patients met the case definition, most (13) arrived at the WTC location on 9/11 or within the following 2 days, and half worked in law enforcement during the 9/1 response. CONCLUSION: An association between HNC and WTC exposure is biologically plausible and should be further investigated. Research to enumerate the risk factor profile for these cancers may contribute to understanding mechanisms by which WTC exposure can contribute to carcinogenesis and to prevention and early detection strategies.

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Head and Neck Cancer in World Trade Center Responders: A Case Series

Abstract

All Science Journal Classification (ASJC) codes

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