Abstract
Chinese hamster V 79 cells heated for 12 hours at 42°C. Surviving cells were cloned and grown as separate cell lines. Nine clones were tested for heat and/or X ray sensitivity after three weeks. Heat sensitivity to 42°C or 45°C was the same as the parent cell line. Also, the radiation sensitivity and response to the combined effects of heat and radiation remained unchanged compared to the original V 79 cell line. Thus, no thermal mutants were selected in the thermal tolerant cell population and the thermal shock received by survivors did not permanently alter the response to heat and/or X rays.
Original language | English (US) |
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Pages (from-to) | 1577-1581 |
Number of pages | 5 |
Journal | International Journal of Radiation Oncology Biology Physics |
Volume | 6 |
Issue number | 11 |
DOIs | |
State | Published - 1980 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Radiation
- Oncology
- Radiology Nuclear Medicine and imaging
- Cancer Research
Keywords
- Clones
- Hyperthermia
- Thermal tolerance