Hemodynamic interventions and the pressure-diameter loop of the left ventricle and the proximal aorta in the conscious dog

Peter L.M. Kerkhof, John K.J. Li

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations

Abstract

The dynamics of the left ventricle (LV) have been extensively investigated. However, most studies refer to steady state conditions. We addressed the beat-to-beat variations resulting from hemodynamic interventions analyzed in the chronically instrumented dog. This approach permits serial studies in the same subject under physiological conditions. In particular we investigated the end-systolic pressure-dimension relationship and characteristics of the proximal aorta. The findings obtained during basal conditions, exercise and pharmacologic intervention indicate that several universal regulatory mechanisms are involved, besides various phenomena that exhibit a substantial degree of variability.

Original languageEnglish (US)
Pages (from-to)3636-3638
Number of pages3
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume26 V
StatePublished - 2004
EventConference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004 - San Francisco, CA, United States
Duration: Sep 1 2004Sep 5 2004

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Keywords

  • Cardiac ventricle
  • Elastance
  • Regulation of heart function

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