Gosselin et al. (2017) reported that a tissue-environment-dependent transcriptional network specifies human microglia identity and that in vitro environments drastically alter the human microglia transcriptome. Recent 3-dimensional culture and human-mouse chimeric brain modeling systems developed using human pluripotent stem cells help us understand the complex properties of human microglia.
|Original language||English (US)|
|Number of pages||3|
|Journal||Cell Stem Cell|
|State||Published - May 7 2020|
All Science Journal Classification (ASJC) codes
- Molecular Medicine
- Cell Biology