High prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic hispanics

M. Dehesa, C. P. Dooley, H. Cohen, P. L. Fitzgibbons, G. I. Perez-Perez, Martin Blaser

Research output: Contribution to journalArticle

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Abstract

In this study, we estimated the prevalence of Helicobacter pylori infection and histologic gastritis in 58 asymptomatic Hispanic adult volunteers (mean age, 41 years; 59% male) by endoscopic biopsy of the upper gastrointestinal tract. Forty-six subjects (79%) were found to harbor H. pylori in gastric biopsies, and all had histologic gastritis. Four other subjects were found to have gastritis in the absence of H. pylori. Similar prevalences of H. pylori and gastritis were noted in all age groups and also in American-born and immigrant Hispanics. Biopsy data and serologic studies of H. pylori antibodies correlated well. We conclude that H. pylori infection is an almost universal finding in the gastric mucosa of asymptomatic adult Hispanics, regardless of age. The clinical significance of these findings is unknown, but we speculate that H. pylori and its associated gastritis could have a role in the high incidence of gastric carcinoma in Hispanic populations.

Original languageEnglish (US)
Pages (from-to)1128-1131
Number of pages4
JournalJournal of Clinical Microbiology
Volume29
Issue number6
StatePublished - Oct 28 1991
Externally publishedYes

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Helicobacter Infections
Gastritis
Hispanic Americans
Helicobacter pylori
Biopsy
Stomach
Upper Gastrointestinal Tract
Gastric Mucosa
Volunteers
Age Groups
Carcinoma
Antibodies
Incidence
Population

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

Cite this

Dehesa, M., Dooley, C. P., Cohen, H., Fitzgibbons, P. L., Perez-Perez, G. I., & Blaser, M. (1991). High prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic hispanics. Journal of Clinical Microbiology, 29(6), 1128-1131.
Dehesa, M. ; Dooley, C. P. ; Cohen, H. ; Fitzgibbons, P. L. ; Perez-Perez, G. I. ; Blaser, Martin. / High prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic hispanics. In: Journal of Clinical Microbiology. 1991 ; Vol. 29, No. 6. pp. 1128-1131.
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Dehesa, M, Dooley, CP, Cohen, H, Fitzgibbons, PL, Perez-Perez, GI & Blaser, M 1991, 'High prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic hispanics', Journal of Clinical Microbiology, vol. 29, no. 6, pp. 1128-1131.

High prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic hispanics. / Dehesa, M.; Dooley, C. P.; Cohen, H.; Fitzgibbons, P. L.; Perez-Perez, G. I.; Blaser, Martin.

In: Journal of Clinical Microbiology, Vol. 29, No. 6, 28.10.1991, p. 1128-1131.

Research output: Contribution to journalArticle

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Dehesa M, Dooley CP, Cohen H, Fitzgibbons PL, Perez-Perez GI, Blaser M. High prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic hispanics. Journal of Clinical Microbiology. 1991 Oct 28;29(6):1128-1131.