@inproceedings{a9edd172a1f64d7f9db40694bddbd673,
title = "High-resolution, 3-D imaging of lumpectomy tissue using optical coherence tomography",
abstract = "Pathology image guidance may enhance the effectiveness of adjuvant radiation treatment by identifying high-risk regions that would benefit from escalated radiation dose and low-risk regions at which little to no radiation dose is necessary. We present 3-D high-resolution optical coherence tomography (OCT) images of breast lumpectomy specimens. Formalin-fixed, paraffin-embedded lumpectomy tissue specimens and mouse breast glands were imaged with OCT in the form of multiple series of 2-D axial depth scans. The computationally-combined series of 2D images forms a reconstructed volume. Ongoing studies will establish whether these images can capture features comparable to the corresponding pathology for localized adjuvant radiation treatment planning.",
author = "Eileen Hwuang and Laura Higgins and Pierce, {Mark C.} and Roberto Droz and Leonard Kim",
note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; 2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014 ; Conference date: 25-04-2014 Through 27-04-2014",
year = "2014",
month = dec,
day = "2",
doi = "10.1109/NEBEC.2014.6972820",
language = "English (US)",
series = "Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
booktitle = "Proceedings - 2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014",
address = "United States",
}