Hippo signaling goes long range

Veronica A. Codelia; Kenneth D. Irvine

doi:10.1016/j.cell.2012.07.020

Hippo signaling goes long range

Veronica A. Codelia, Kenneth D. Irvine

Research output: Contribution to journal › Short survey › peer-review

23 Scopus citations

Abstract

The Hippo-YAP pathway regulates organ size by modulating cell proliferation and apoptosis. Yu et al. now reveal that G-protein-coupled receptors act upstream of the transcriptional coactivators YAP/TAZ. This study reinforces the connection between the actin cytoskeleton and Hippo pathway activity and identifies a class of secreted extracellular regulators of YAP/TAZ activity.

Original language	English (US)
Pages (from-to)	669-670
Number of pages	2
Journal	Cell
Volume	150
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2012.07.020
State	Published - Aug 17 2012

All Science Journal Classification (ASJC) codes

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/j.cell.2012.07.020

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title = "Hippo signaling goes long range",

abstract = "The Hippo-YAP pathway regulates organ size by modulating cell proliferation and apoptosis. Yu et al. now reveal that G-protein-coupled receptors act upstream of the transcriptional coactivators YAP/TAZ. This study reinforces the connection between the actin cytoskeleton and Hippo pathway activity and identifies a class of secreted extracellular regulators of YAP/TAZ activity.",

author = "Codelia, {Veronica A.} and Irvine, {Kenneth D.}",

year = "2012",

month = aug,

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doi = "10.1016/j.cell.2012.07.020",

language = "English (US)",

volume = "150",

pages = "669--670",

journal = "Cell",

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publisher = "Cell Press",

number = "4",

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TY - JOUR

T1 - Hippo signaling goes long range

AU - Codelia, Veronica A.

AU - Irvine, Kenneth D.

PY - 2012/8/17

Y1 - 2012/8/17

N2 - The Hippo-YAP pathway regulates organ size by modulating cell proliferation and apoptosis. Yu et al. now reveal that G-protein-coupled receptors act upstream of the transcriptional coactivators YAP/TAZ. This study reinforces the connection between the actin cytoskeleton and Hippo pathway activity and identifies a class of secreted extracellular regulators of YAP/TAZ activity.

AB - The Hippo-YAP pathway regulates organ size by modulating cell proliferation and apoptosis. Yu et al. now reveal that G-protein-coupled receptors act upstream of the transcriptional coactivators YAP/TAZ. This study reinforces the connection between the actin cytoskeleton and Hippo pathway activity and identifies a class of secreted extracellular regulators of YAP/TAZ activity.

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UR - http://www.scopus.com/inward/citedby.url?scp=84865264557&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2012.07.020

DO - 10.1016/j.cell.2012.07.020

M3 - Short survey

C2 - 22901800

AN - SCOPUS:84865264557

SN - 0092-8674

VL - 150

SP - 669

EP - 670

JO - Cell

JF - Cell

IS - 4

ER -

Hippo signaling goes long range

Abstract

All Science Journal Classification (ASJC) codes

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