Histologic examination of removed transplanted kidneys

Norman Ende, J. C. Pierce

Research output: Contribution to journalArticle

Abstract

A retrospective study is being conducted on all kidneys exchanged between institutions affiliated with the Southeastern Regional Organ Procurement Program. After having been nephrectomized or removed at autopsy, the first 76 kidneys of this study were histologically examined without knowledge of the clinical history. Vascular, glomerular, cellular infiltration and other morphologic changes were evaluated and the degree of morphologic alteration was graded from I to IV. While 39 kidneys showed adequate histologic evidence of rejection by the recipient, 9 kidneys showed morphologic changes which made the relation to the rejection hypothesis ambiguous. Twenty eight kidneys did not show sufficient histologic change to support the necessity for removal due to rejection by the host. Of this latter group of minimal or no histologic evidence of rejection, 11 were nephrectomized and 17 were obtained at autopsy. The study suggests that a significant number of transplanted cadaver kidneys were lost from causes other than rejection.

Original languageEnglish (US)
JournalAmerican Journal of Pathology
Volume78
Issue number1
StatePublished - Jan 1 1975

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Kidney
Autopsy
Tissue and Organ Procurement
Cadaver
Blood Vessels
Retrospective Studies

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

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Histologic examination of removed transplanted kidneys. / Ende, Norman; Pierce, J. C.

In: American Journal of Pathology, Vol. 78, No. 1, 01.01.1975.

Research output: Contribution to journalArticle

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