Human Milk Bacterial and Glycosylation Patterns Differ by Delivery Mode

Marina Hoashi, Lawrence Meche, Lara K. Mahal, Elizabeth Bakacs, Deanna Nardella, Frederick Naftolin, Naomi Bar-Yam, Maria G. Dominguez-Bello

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Mammals have evolved to nourish their offspring exclusively with maternal milk for around half of the lactation period, a crucial developmental window. In view of oral-breast contact during lactation and the differences in oral microbiota between cesarean section (C-section) and vaginally delivered infants, we expected differences in milk composition by delivery mode. We performed a cross-sectional study of banked human milk and found changes related to time since delivery in bacterial abundance and glycosylation patterns only in milk from women who delivered vaginally. The results warrant further research into the effects of delivery mode on milk microbes, milk glycosylation, and postpartum infant development.

Original languageEnglish (US)
Pages (from-to)902-907
Number of pages6
JournalReproductive Sciences
Issue number7
StatePublished - Jul 1 2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology


  • C-section
  • breast milk
  • human microbiome
  • milk glycosylation


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