Abstract
We examined the prevalence of infection with human papillomavirus (HPV) and HIV in a cohort of young gay, bisexual, and other men who have sex with men [sexual minority men (SMM)]. HPV vaccination uptake was assessed; HIV antibody testing was performed and genetic testing for oral and anal HPV infection was undertaken. We examined both HPV vaccination and infection in relation to key demographic and structural variables. Participants (n = 486) were on average 23 years old; 70% identified as a member of a racial/ethnic minority group, and 7% identified as transgender females. Only 18.1% of the participants indicated having received the full dosage of HPV vaccination and 45.1% were unvaccinated. Slightly over half the participants (58.6%) were infected with HPV, with 58.1% testing positive for anal infection and 8.8% for oral infection. HIV seropositivity was associated with infection to oral HPV [adjusted odds ratio (AOR) = 4.03] and vaccine-preventable HPV, whereas both neighborhood-level poverty (AOR = 1.68) and HIV infection (AOR = 31.13) were associated with anal infection to HPV (AOR = 1.68). Prevalence of HPV infection is high among unvaccinated young SMM, despite the availability and eligibility for vaccination. HPV infection adds further health burden to these populations and is particularly concerning for those who are HIV positive as HIV infection increases the risk of developing HPV-related cancers. These findings underscore a missed prevention opportunity for an at-risk and underserved population and suggest the need for active strategies to increase HPV vaccination uptake in young SMM before the onset of sexual behavior.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 149-156 |
| Number of pages | 8 |
| Journal | AIDS patient care and STDs |
| Volume | 33 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 2019 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Public Health, Environmental and Occupational Health
- Infectious Diseases
Keywords
- HIV
- HPV
- cancer
- emerging adulthood
- gay and bisexual men
- vaccination
Cite this
}
Human Papillomavirus Vaccination and Infection in Young Sexual Minority Men : The P18 Cohort Study. / Halkitis, Perry N.; Valera, Pamela; Loschiavo, Caleb E.; Goldstone, Stephen E.; Kanztanou, Maria; Maiolatesi, Anthony J.; Ompad, Danielle C.; Greene, Richard E.; Kapadia, Farzana.
In: AIDS patient care and STDs, Vol. 33, No. 4, 04.2019, p. 149-156.Research output: Contribution to journal › Article
TY - JOUR
T1 - Human Papillomavirus Vaccination and Infection in Young Sexual Minority Men
T2 - The P18 Cohort Study
AU - Halkitis, Perry N.
AU - Valera, Pamela
AU - Loschiavo, Caleb E.
AU - Goldstone, Stephen E.
AU - Kanztanou, Maria
AU - Maiolatesi, Anthony J.
AU - Ompad, Danielle C.
AU - Greene, Richard E.
AU - Kapadia, Farzana
PY - 2019/4
Y1 - 2019/4
N2 - We examined the prevalence of infection with human papillomavirus (HPV) and HIV in a cohort of young gay, bisexual, and other men who have sex with men [sexual minority men (SMM)]. HPV vaccination uptake was assessed; HIV antibody testing was performed and genetic testing for oral and anal HPV infection was undertaken. We examined both HPV vaccination and infection in relation to key demographic and structural variables. Participants (n = 486) were on average 23 years old; 70% identified as a member of a racial/ethnic minority group, and 7% identified as transgender females. Only 18.1% of the participants indicated having received the full dosage of HPV vaccination and 45.1% were unvaccinated. Slightly over half the participants (58.6%) were infected with HPV, with 58.1% testing positive for anal infection and 8.8% for oral infection. HIV seropositivity was associated with infection to oral HPV [adjusted odds ratio (AOR) = 4.03] and vaccine-preventable HPV, whereas both neighborhood-level poverty (AOR = 1.68) and HIV infection (AOR = 31.13) were associated with anal infection to HPV (AOR = 1.68). Prevalence of HPV infection is high among unvaccinated young SMM, despite the availability and eligibility for vaccination. HPV infection adds further health burden to these populations and is particularly concerning for those who are HIV positive as HIV infection increases the risk of developing HPV-related cancers. These findings underscore a missed prevention opportunity for an at-risk and underserved population and suggest the need for active strategies to increase HPV vaccination uptake in young SMM before the onset of sexual behavior.
AB - We examined the prevalence of infection with human papillomavirus (HPV) and HIV in a cohort of young gay, bisexual, and other men who have sex with men [sexual minority men (SMM)]. HPV vaccination uptake was assessed; HIV antibody testing was performed and genetic testing for oral and anal HPV infection was undertaken. We examined both HPV vaccination and infection in relation to key demographic and structural variables. Participants (n = 486) were on average 23 years old; 70% identified as a member of a racial/ethnic minority group, and 7% identified as transgender females. Only 18.1% of the participants indicated having received the full dosage of HPV vaccination and 45.1% were unvaccinated. Slightly over half the participants (58.6%) were infected with HPV, with 58.1% testing positive for anal infection and 8.8% for oral infection. HIV seropositivity was associated with infection to oral HPV [adjusted odds ratio (AOR) = 4.03] and vaccine-preventable HPV, whereas both neighborhood-level poverty (AOR = 1.68) and HIV infection (AOR = 31.13) were associated with anal infection to HPV (AOR = 1.68). Prevalence of HPV infection is high among unvaccinated young SMM, despite the availability and eligibility for vaccination. HPV infection adds further health burden to these populations and is particularly concerning for those who are HIV positive as HIV infection increases the risk of developing HPV-related cancers. These findings underscore a missed prevention opportunity for an at-risk and underserved population and suggest the need for active strategies to increase HPV vaccination uptake in young SMM before the onset of sexual behavior.
KW - HIV
KW - HPV
KW - cancer
KW - emerging adulthood
KW - gay and bisexual men
KW - vaccination
UR - http://www.scopus.com/inward/record.url?scp=85064007200&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85064007200&partnerID=8YFLogxK
U2 - 10.1089/apc.2018.0276
DO - 10.1089/apc.2018.0276
M3 - Article
C2 - 30932696
AN - SCOPUS:85064007200
VL - 33
SP - 149
EP - 156
JO - AIDS Patient Care and STDs
JF - AIDS Patient Care and STDs
SN - 1087-2914
IS - 4
ER -