Humoral abnormalities in three patients with idiopathic chronic polyneuropathy

P. K. Coyle, S. E. Schutzer, A. B. Sterman, N. Peress, F. Miller

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Three patients with chronic polyneuropathy of unknown origin were found to have abnormalities in humoral immunity characterized by anti-nerve antibodies, cold-reactive anti-lymphocyte antibodies, and circulating immune complexes. In two patients, clinical improvement coincided with plasmapheresis and removal of the anti-nerve antibodies. Certain patients with idiopathic peripheral neuropathy may benefit from therapy directed at correcting immunologic abnormalities.

Original languageEnglish (US)
Pages (from-to)248-250
Number of pages3
JournalNew York State Journal of Medicine
Issue number6
StatePublished - 1985
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine


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