Hydroxylated polymethoxyflavones and methylated flavonoids in sweet orange (Citrus sinensis) peel

Shiming Li, Chih Yu Lo, Chi Tang Ho

Research output: Contribution to journalArticlepeer-review

253 Scopus citations


Polymethoxyflavones (PMFs) from citrus genus have been of particular interest because of their broad spectrum of biological activities, including antiinflammatory, anticarcinogenic, and antiatherogenic properties. There have been increasing interests in the exploration of health beneficial properties of PMFs in citrus fruits. Therefore, the isolation and characterization of PMFs from sweet orange (Citrus sinensis) peel will lead to new applications of the byproducts from orange juice processes and other orange consumption in nutraceutical and pharmaceutical products. In our study, eight hydroxylated PMFs, six PMFs, one polymethoxyflavanone, one hydroxylated polymethoxyflavanone, and two hydroxylated polymethoxychalcones were isolated from sweet orange peel and their structures were elucidated by various MS, UV, and different NMR techniques. Some of the hydroxylated PMFs and chalcones are newly isolated from sweet orange peel.

Original languageEnglish (US)
Pages (from-to)4176-4185
Number of pages10
JournalJournal of agricultural and food chemistry
Issue number12
StatePublished - Jun 14 2006

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Agricultural and Biological Sciences(all)


  • Chalcones
  • Hydroxylated polymethoxyflavones
  • Isolation and characterization
  • Polymethoxyflavonoids
  • Sweet orange peel (Citrus sinensis)

Fingerprint Dive into the research topics of 'Hydroxylated polymethoxyflavones and methylated flavonoids in sweet orange (Citrus sinensis) peel'. Together they form a unique fingerprint.

Cite this