Hyperphosphatemia and hypocalcemia accompanying rapid cell lysis in a patient with Burkitt's lymphoma and Burkitt cell leukemia

E. C. Cadman, W. B. Lundberg, J. R. Bertino

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Abstract

Hyperphosphatemia, hypocalcemia and acute oliguric renal failure resulting from uric acid nephropathy developed in a patient with Burkitt's lymphoma and Burkitt cell leukemia after effective chemotherapy. A review of other reported cases in which the patients had similar metabolic abnormalities is presented, and the pathophysiology is discussed. The clinical setting in which these metabolic developments are most likely to occur is defined, and an approach for their prevention and management is presented.

Original languageEnglish (US)
Pages (from-to)283-290
Number of pages8
JournalThe American Journal of Medicine
Volume62
Issue number2
DOIs
StatePublished - Jan 1 1977
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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