Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitro-camptothecin

Eric Rubin, Panayotis Pantazis, Ajit Bharti, Deborah Toppmeyer, Beppino Giovanella, Donald Kufe

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Immunology and Microbiology

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Biochemistry, Genetics and Molecular Biology

Medicine and Dentistry

Pharmacology, Toxicology and Pharmaceutical Science