Identification of extrachromosomal DNA in hematolymphoid cells of chickens and mice

Arthur H. Bertelsen, M. Zafri Humayun, Andrea Lippman, Mark G. Rush

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Extrachromosomal DNA of heterogeneous size has been isolated from bursal lymphocytes and splenocytes of five week old chickens, and from splenocytes of mice. This DNA contains covalently closed circles, open circles, and open circles with tails. Open circular molecules with and without tails are more frequent than covalently closed species, and the total number of small circular DNA molecules per cell is in the range of 100-200 copies.

Original languageEnglish (US)
Pages (from-to)977-984
Number of pages8
JournalBiochemical and Biophysical Research Communications
Volume105
Issue number3
DOIs
StatePublished - Apr 14 1982
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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