Implant retrieval - a multi centre, multidisciplinary study

The actual performance of implants in human patients was studied by retrieving seven implants from total knee and hip replacements. For each implant, there was consistency in the histomorphometric data obtained by the different laboratories with respect to the bone changes present. Differences were seen between the tissue reactions to the seven implant components although the analysis provided direct evidence that a limited number of cross sections can give basic information about the actual performance of an implant. The chief benefit from pooling the expertise of several laboratories to examine the same devices is the added value.