Abstract
Neutrophils from a patient with chronic myelogenous leukemia and typically low leukocyte alkaline phosphatase (LAP) activity markedly increased in LAP content following transfusion to and circulation in an infected neutropenic recipient. Incubation of the recipient's serum and plasma with normal neutrophils failed to alter their LAP activity. This observation suggests that LAP activity is inducible by as yet unknown "environmental" factors, and possible mechanisms for this are discussed.
Original language | English (US) |
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Pages (from-to) | 519-522 |
Number of pages | 4 |
Journal | The American Journal of Medicine |
Volume | 66 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1979 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Medicine(all)