Inhibition by 2′,3′-dideoxythymidine of retroviral infection of mouse and human cells

Philip Furmanski; Gerard J. Bourguignon; Christopher S. Bolles; Jeanne D. Corombos; Mukkattu R. Das

doi:10.1016/0304-3835(80)90146-9

Inhibition by 2′,3′-dideoxythymidine of retroviral infection of mouse and human cells

Philip Furmanski, Gerard J. Bourguignon, Christopher S. Bolles, Jeanne D. Corombos, Mukkattu R. Das

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Infection of mouse and human cells with type C murine leukemia/sarcoma viruses was inhibited by the nucleoside analogue 2′,3′-dideoxythymidine (ddT). Cell growth and virus synthesis by previously infected cells were not affected by the analogue. Infection of rat cells with murine retroviruses was not inhibited by ddT.

Original language	English (US)
Pages (from-to)	307-315
Number of pages	9
Journal	Cancer Letters
Volume	8
Issue number	4
DOIs	https://doi.org/10.1016/0304-3835(80)90146-9
State	Published - Feb 1980
Externally published	Yes

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

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10.1016/0304-3835(80)90146-9

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@article{8129484be2f24d82846c424d45d43361,

title = "Inhibition by 2′,3′-dideoxythymidine of retroviral infection of mouse and human cells",

abstract = "Infection of mouse and human cells with type C murine leukemia/sarcoma viruses was inhibited by the nucleoside analogue 2′,3′-dideoxythymidine (ddT). Cell growth and virus synthesis by previously infected cells were not affected by the analogue. Infection of rat cells with murine retroviruses was not inhibited by ddT.",

author = "Philip Furmanski and Bourguignon, {Gerard J.} and Bolles, {Christopher S.} and Corombos, {Jeanne D.} and Das, {Mukkattu R.}",

note = "Funding Information: This study was supported by National Cancer Institute grant CA 14100 and contract NOl-CP-33347 from the Virus Cancer Program, National Cancer Institute and institutional grants from the United Foundation of Detroit and the Suzanne Korman Morton Cancer Research Laboratory.",

year = "1980",

month = feb,

doi = "10.1016/0304-3835(80)90146-9",

language = "English (US)",

volume = "8",

pages = "307--315",

journal = "Cancer Letters",

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T1 - Inhibition by 2′,3′-dideoxythymidine of retroviral infection of mouse and human cells

AU - Furmanski, Philip

AU - Bourguignon, Gerard J.

AU - Bolles, Christopher S.

AU - Corombos, Jeanne D.

AU - Das, Mukkattu R.

N1 - Funding Information: This study was supported by National Cancer Institute grant CA 14100 and contract NOl-CP-33347 from the Virus Cancer Program, National Cancer Institute and institutional grants from the United Foundation of Detroit and the Suzanne Korman Morton Cancer Research Laboratory.

PY - 1980/2

Y1 - 1980/2

N2 - Infection of mouse and human cells with type C murine leukemia/sarcoma viruses was inhibited by the nucleoside analogue 2′,3′-dideoxythymidine (ddT). Cell growth and virus synthesis by previously infected cells were not affected by the analogue. Infection of rat cells with murine retroviruses was not inhibited by ddT.

AB - Infection of mouse and human cells with type C murine leukemia/sarcoma viruses was inhibited by the nucleoside analogue 2′,3′-dideoxythymidine (ddT). Cell growth and virus synthesis by previously infected cells were not affected by the analogue. Infection of rat cells with murine retroviruses was not inhibited by ddT.

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JO - Cancer Letters

JF - Cancer Letters

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ER -

Inhibition by 2′,3′-dideoxythymidine of retroviral infection of mouse and human cells

Abstract

All Science Journal Classification (ASJC) codes

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