Insecticide solvents: Interference with insecticidal action

L. B. Brattsten, C. F. Wilkinson

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Several commercial solvent mixtures commonly used as insecticide carriers in spray formulations increase by more than threefold the microsomal N-demethylation of p-chloro N-methylaniline in midgut preparations of southern army-worm (Spodoptera eridania) larvae exposed orally to the test solvents. Under laboratory conditions, the same solvent mixtures exhibit a protective action against the in vivo toxicity of the insecticide carbaryl to the larvae. The data are discussed with respect to possible solvent-insecticide interactions occurring under field conditions and, more broadly, to potential toxicological hazards of these solvents to humans.

Original languageEnglish (US)
Pages (from-to)1211-1213
Number of pages3
Issue number4295
StatePublished - 1977
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General


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