Insights on Variance Estimation for Blocked and Matched Pairs Designs

Evaluating blocked randomized experiments from a potential outcomes perspective has two primary branches of work. The first focuses on larger blocks, with multiple treatment and control units in each block. The second focuses on matched pairs, with a single treatment and control unit in each block. These literatures not only provide different estimators for the standard errors of the estimated average impact, but they are also built on different sets of assumptions. Neither literature handles cases with blocks of varying size that contain singleton treatment or control units, a case which can occur in a variety of contexts, such as with different forms of matching or poststratification. In this article, we reconcile the literatures by carefully examining the performance of variance estimators under several different frameworks. We then use these insights to derive novel variance estimators for experiments containing blocks of different sizes.