Integrating genomic information with protein sequence and 3D atomic level structure at the RCSB protein data bank

Andreas Prlić, Tara Kalro, Roshni Bhattacharya, Cole Christie, Stephen K. Burley, Peter W. Rose

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The Protein Data Bank (PDB) now contains more than 120,000 three-dimensional (3D) structures of biological macromolecules. To allow an interpretation of how PDB data relates to other publicly available annotations, we developed a novel data integration platform that maps 3D structural information across various datasets. This integration bridges from the human genome across protein sequence to 3D structure space. We developed novel software solutions for data management and visualization, while incorporating new libraries for web-based visualization using SVG graphics.

Original languageEnglish (US)
Pages (from-to)3833-3835
Number of pages3
JournalBioinformatics
Volume32
Issue number24
DOIs
StatePublished - Dec 15 2016

All Science Journal Classification (ASJC) codes

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

Fingerprint Dive into the research topics of 'Integrating genomic information with protein sequence and 3D atomic level structure at the RCSB protein data bank'. Together they form a unique fingerprint.

Cite this