Integrin-collagen complex: A metal-glutamate handshake

Jordi Bella, Helen M. Berman

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations

Abstract

The recently determined crystal structure of the complex between an integrin I domain and a synthetic collagen peptide shows a collagen triple- helix engaged in specific macromolecular recognition and binding. This structure confirms a previously proposed binding mechanism for integrin I domains and has important implications for integrin activation and signalling.

Original languageEnglish (US)
Pages (from-to)R121-R126
JournalStructure
Volume8
Issue number6
DOIs
StatePublished - Jun 1 2000

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Molecular Biology

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