Intravenous Infusion of Zidovudine (AZT) in Children with HIV Infection

Harold W. Lischner, Stephen A. Raphael, David P. Schor, Margaret C. Fisher, Adamadia Deforest, James J. Riviello, Leroy R. Sharer, Leon G. Epstein, Philip A. Pizzo, Pim Brouwers, David G. Poplack, Frank Balis, Howard Moss

Research output: Contribution to journalLetterpeer-review

1 Scopus citations


To the Editor: Preliminary reports suggest that zidovudine (AZT) has a positive risk-to-benefit ratio in some children with human immunodeficiency virus (HIV) infection. We believe, however, that Pizzo et al. (Oct. 6 issue)1 did not provide data to justify their conclusion to that effect. Information is lacking regarding (1) the extent to which entry into the study resulted in changes in the home environment or care, nutritional or other therapy, supportive services to the child and family, or educational opportunities; (2) probable differences in the timing and settings (e.g., in relation to stressful associations) of the initial as compared with…

Original languageEnglish (US)
Pages (from-to)805-806
Number of pages2
JournalNew England Journal of Medicine
Issue number12
StatePublished - Mar 23 1989

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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