Abstract
We investigate the settling of spherical particles through a pinching gap created by a cylindrical obstacle and a vertical wall. These macroscopic experiments capture the essence of pinched-flow-fractionation in microfluidics and highlight its deterministic nature. In the absence of pinching, we observe asymmetric trajectories consistent with a hard-core model of particle-obstacle repulsion that leads to separative lateral displacement. Then, we show that pinching promotes the onset of these short-range repulsion forces, amplifying the relative separation in the outgoing trajectory of different-size particles. Inertia effects, however, tend to reduce such relative separation and lead to a more complex behavior.
| Original language | English (US) |
|---|---|
| Article number | 064102 |
| Journal | Applied Physics Letters |
| Volume | 99 |
| Issue number | 6 |
| DOIs | |
| State | Published - Aug 8 2011 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Physics and Astronomy (miscellaneous)
Cite this
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Irreversibility and pinching in deterministic particle separation. / Luo, Mingxiang; Sweeney, Francis; Risbud, Sumedh R.; Drazer, German; Frechette, Joelle.
In: Applied Physics Letters, Vol. 99, No. 6, 064102, 08.08.2011.Research output: Contribution to journal › Article
TY - JOUR
T1 - Irreversibility and pinching in deterministic particle separation
AU - Luo, Mingxiang
AU - Sweeney, Francis
AU - Risbud, Sumedh R.
AU - Drazer, German
AU - Frechette, Joelle
PY - 2011/8/8
Y1 - 2011/8/8
N2 - We investigate the settling of spherical particles through a pinching gap created by a cylindrical obstacle and a vertical wall. These macroscopic experiments capture the essence of pinched-flow-fractionation in microfluidics and highlight its deterministic nature. In the absence of pinching, we observe asymmetric trajectories consistent with a hard-core model of particle-obstacle repulsion that leads to separative lateral displacement. Then, we show that pinching promotes the onset of these short-range repulsion forces, amplifying the relative separation in the outgoing trajectory of different-size particles. Inertia effects, however, tend to reduce such relative separation and lead to a more complex behavior.
AB - We investigate the settling of spherical particles through a pinching gap created by a cylindrical obstacle and a vertical wall. These macroscopic experiments capture the essence of pinched-flow-fractionation in microfluidics and highlight its deterministic nature. In the absence of pinching, we observe asymmetric trajectories consistent with a hard-core model of particle-obstacle repulsion that leads to separative lateral displacement. Then, we show that pinching promotes the onset of these short-range repulsion forces, amplifying the relative separation in the outgoing trajectory of different-size particles. Inertia effects, however, tend to reduce such relative separation and lead to a more complex behavior.
UR - http://www.scopus.com/inward/record.url?scp=84860400050&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84860400050&partnerID=8YFLogxK
U2 - 10.1063/1.3617425
DO - 10.1063/1.3617425
M3 - Article
AN - SCOPUS:84860400050
VL - 99
JO - Applied Physics Letters
JF - Applied Physics Letters
SN - 0003-6951
IS - 6
M1 - 064102
ER -