Abstract
A method for integrating porous polymer membranes such as polycarbonate, polyethersulfone and polyethylene terephthalate to microfluidic devices is described. The use of 3-aminopropyltriethoxysilane as a chemical crosslinking agent was extended to integrate membranes with PDMS and glass microfluidic channels. A strong, irreversible bond between the membranes and microfluidic structure was achieved. The bonding strength in the APTES treated devices was significantly greater than in devices fabricated using either a PDMS "glue" or two-part epoxy bonding method. Evaluation of a filtering microdevice and the pore structure via SEM indicates the APTES conjugation does not significantly alter the membrane transport function and pore morphology.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 548-552 |
| Number of pages | 5 |
| Journal | Lab on a Chip |
| Volume | 10 |
| Issue number | 5 |
| DOIs | |
| State | Published - 2010 |
All Science Journal Classification (ASJC) codes
- Bioengineering
- Biochemistry
- General Chemistry
- Biomedical Engineering