@inbook{704e1c724a5646eb940dfc8ed7db91f0,
title = "Ketogenic Diet, Inflammation, and Epilepsy",
abstract = "Ketogenic diet is a high-fat, low-carbohydrate metabolic intervention that has been in use for the treatment of epilepsy for almost a hundred years. This metabolic intervention affects epilepsy through multiple mechanisms, which combine to exert potent anti-inflammatory activity. Thereby, ketogenic diet not only affects seizures per se but also has the potential to attenuate or prevent the development of epilepsy and its progression. This chapter will focus on novel disease-modifying properties of ketogenic diet therapy and will discuss therapeutic challenges and opportunities.",
keywords = "Adenosine, Disease modification, Epileptogenesis, Metabolic therapy, Metabolism",
author = "Detlev Boison",
note = "Funding Information: The author wishes to thank the following agencies for generous research funding: the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Mental Health (NIMH), the US Department of Defense (DoD), the Epilepsy Foundation, and Citizens United for the Research in Epilepsy (CURE). Publisher Copyright: {\textcopyright} 2021, Springer Nature Switzerland AG.",
year = "2021",
doi = "10.1007/978-3-030-67403-8_8",
language = "English (US)",
series = "Progress in Inflammation Research",
publisher = "Springer Nature",
pages = "185--201",
booktitle = "Progress in Inflammation Research",
address = "United States",
}