Limit cycle model of apneic breathing in neonates

N. Krawciw, G. Drzewiecki, B. Ostfeld, S. Burke, T. Hegyi, M. Hiatt

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The breathing patterns of premature infants are known to change with state. A common pattern is cycling or periodic breathing where regular breathing is interspersed with apneic episodes. Preterm infants are monitored noninvasively using a pneumoimpedance technique to obtain data records of apneic breathing. A mathematical model of breathing is developed that employs a limit cycle nonlinear oscillator. Random drive is introduced to the oscillator frequency and amplitude, corresponding to deviations observed in the data. Finally, a state parameter is altered to cause a loss of oscillations. Variation of the parameter is found to alter the tendency to apnea. This, together with the fluctuations in the amplitude of breathing, determines whether an apnea actually occurs.

Original languageEnglish (US)
Title of host publicationBiomedical Engineering Perspectives
Subtitle of host publicationHealth Care Technologies for the 1990's and Beyond
PublisherPubl by IEEE
Pages1392-1393
Number of pages2
Editionpt 3
ISBN (Print)0879425598
StatePublished - 1990
EventProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Philadelphia, PA, USA
Duration: Nov 1 1990Nov 4 1990

Publication series

NameProceedings of the Annual Conference on Engineering in Medicine and Biology
Numberpt 3
ISSN (Print)0589-1019

Other

OtherProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityPhiladelphia, PA, USA
Period11/1/9011/4/90

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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