Lipid composition and viscosity of parotid saliva in Sjögren syndrome in man

B. L. Slomiany; M. Kosmala; C. Nadziejko; V. L.N. Murty; K. Gwozdzinski; A. Slomiany; I. D. Mandel

doi:10.1016/0003-9969(86)90100-7

Lipid composition and viscosity of parotid saliva in Sjögren syndrome in man

B. L. Slomiany, M. Kosmala, C. Nadziejko, V. L.N. Murty, K. Gwozdzinski, A. Slomiany, I. D. Mandel

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Extraction of the dialysed and lyophilized saliva of patients with this syndrome by chloroform-methanol yielded 15.9 ± 2.4 mg of lipid/100ml of secretion, a level 2-times higher than in normal individuals. The saliva of such patients also had 3-times more glycolipid and 20-times more phospholipid than normal, but differences in the content of neutral lipids were less apparent. The neutral lipids, however, had higher proportions of glycerides, and lower proportions of cholesterol and cholesteryl esters than normal. Viscosity measurements, made with a cone/plate viscometer at shear rates between 1.15 and 230 s^-1, revealed similarities between the saliva of normal individuals and Sjögren's syndrome.

Original language	English (US)
Pages (from-to)	699-702
Number of pages	4
Journal	Archives of Oral Biology
Volume	31
Issue number	10
DOIs	https://doi.org/10.1016/0003-9969(86)90100-7
State	Published - 1986
Externally published	Yes

All Science Journal Classification (ASJC) codes

Otorhinolaryngology
Dentistry(all)
Cell Biology

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10.1016/0003-9969(86)90100-7

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@article{4afecf4777d948d0859557fb1c383fce,

title = "Lipid composition and viscosity of parotid saliva in Sj{\"o}gren syndrome in man",

abstract = "Extraction of the dialysed and lyophilized saliva of patients with this syndrome by chloroform-methanol yielded 15.9 ± 2.4 mg of lipid/100ml of secretion, a level 2-times higher than in normal individuals. The saliva of such patients also had 3-times more glycolipid and 20-times more phospholipid than normal, but differences in the content of neutral lipids were less apparent. The neutral lipids, however, had higher proportions of glycerides, and lower proportions of cholesterol and cholesteryl esters than normal. Viscosity measurements, made with a cone/plate viscometer at shear rates between 1.15 and 230 s-1, revealed similarities between the saliva of normal individuals and Sj{\"o}gren's syndrome.",

author = "Slomiany, {B. L.} and M. Kosmala and C. Nadziejko and Murty, {V. L.N.} and K. Gwozdzinski and A. Slomiany and Mandel, {I. D.}",

note = "Funding Information: Acknowledgement-Thisw ork was supported by USPHS Grant DE no. 05666-06 from the National Institute of Dental Research, National Institute of Health.",

year = "1986",

doi = "10.1016/0003-9969(86)90100-7",

language = "English (US)",

volume = "31",

pages = "699--702",

journal = "Archives of Oral Biology",

issn = "0003-9969",

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number = "10",

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TY - JOUR

T1 - Lipid composition and viscosity of parotid saliva in Sjögren syndrome in man

AU - Slomiany, B. L.

AU - Kosmala, M.

AU - Nadziejko, C.

AU - Murty, V. L.N.

AU - Gwozdzinski, K.

AU - Slomiany, A.

AU - Mandel, I. D.

N1 - Funding Information: Acknowledgement-Thisw ork was supported by USPHS Grant DE no. 05666-06 from the National Institute of Dental Research, National Institute of Health.

PY - 1986

Y1 - 1986

N2 - Extraction of the dialysed and lyophilized saliva of patients with this syndrome by chloroform-methanol yielded 15.9 ± 2.4 mg of lipid/100ml of secretion, a level 2-times higher than in normal individuals. The saliva of such patients also had 3-times more glycolipid and 20-times more phospholipid than normal, but differences in the content of neutral lipids were less apparent. The neutral lipids, however, had higher proportions of glycerides, and lower proportions of cholesterol and cholesteryl esters than normal. Viscosity measurements, made with a cone/plate viscometer at shear rates between 1.15 and 230 s-1, revealed similarities between the saliva of normal individuals and Sjögren's syndrome.

AB - Extraction of the dialysed and lyophilized saliva of patients with this syndrome by chloroform-methanol yielded 15.9 ± 2.4 mg of lipid/100ml of secretion, a level 2-times higher than in normal individuals. The saliva of such patients also had 3-times more glycolipid and 20-times more phospholipid than normal, but differences in the content of neutral lipids were less apparent. The neutral lipids, however, had higher proportions of glycerides, and lower proportions of cholesterol and cholesteryl esters than normal. Viscosity measurements, made with a cone/plate viscometer at shear rates between 1.15 and 230 s-1, revealed similarities between the saliva of normal individuals and Sjögren's syndrome.

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ER -

Lipid composition and viscosity of parotid saliva in Sjögren syndrome in man

Abstract

All Science Journal Classification (ASJC) codes

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