Lipid composition and viscosity of parotid saliva in Sjögren syndrome in man

B. L. Slomiany, M. Kosmala, C. Nadziejko, V. L.N. Murty, K. Gwozdzinski, A. Slomiany, I. D. Mandel

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Extraction of the dialysed and lyophilized saliva of patients with this syndrome by chloroform-methanol yielded 15.9 ± 2.4 mg of lipid/100ml of secretion, a level 2-times higher than in normal individuals. The saliva of such patients also had 3-times more glycolipid and 20-times more phospholipid than normal, but differences in the content of neutral lipids were less apparent. The neutral lipids, however, had higher proportions of glycerides, and lower proportions of cholesterol and cholesteryl esters than normal. Viscosity measurements, made with a cone/plate viscometer at shear rates between 1.15 and 230 s-1, revealed similarities between the saliva of normal individuals and Sjögren's syndrome.

Original languageEnglish (US)
Pages (from-to)699-702
Number of pages4
JournalArchives of Oral Biology
Volume31
Issue number10
DOIs
StatePublished - 1986
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Dentistry(all)
  • Cell Biology

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