Long-term regulation of hepatic glutaminase and the urea cycle enzymes

Research output: Chapter in Book/Report/Conference proceedingChapter


Glutamine is not a dietary essential amino acid, but it does play an important role within the body, and recent developments in the treatment of several pathological states have resulted in the provision of large amounts of dietary glutamine, either enterally or parenterally.13 A major fate of glutamine within the body is catabolism via the hepatic pathways of gluconeogenesis and urea synthesis. This review focuses on the long-term regulation of glutamine catabolism within the liver through changes in the activities of phosphate-activated glutaminase and the urea cycle enzymes.

Original languageEnglish (US)
Title of host publicationNutrition and Gene Expression
PublisherCRC Press
Number of pages18
ISBN (Electronic)9781351083560
ISBN (Print)0849369614, 9781315896014
StatePublished - Jan 1 2018

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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