Mammalian septins nomenclature

Ian G. Macara, Richard Baldarelli, Christine M. Field, Michael Glotzer, Yasuhide Hayashi, Shu Chan Hsu, Mary B. Kennedy, Makoto Kinoshita, Mark Longtine, Claudia Low, Lois J. Maltais, Louise McKenzie, Timothy J. Mitchison, Toru Nishikawa, Makoto Noda, Elizabeth M. Petty, Mark Peifer, John R. Pringle, Phillip J. Robinson, Dagmar RothS. E. Hilary Russell, Heidi Stuhlmann, Manami Tanaka, Tomoo Tanaka, William S. Trimble, Jerry Ware, Nancy J. Zeleznik-Le, Barbara Zieger

Research output: Contribution to journalReview articlepeer-review

108 Scopus citations


There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and distinct names given to splice variants of the same gene. Moreover, some names are based on those of yeast or Drosophila septins that are not the closest homologues. Therefore, we suggest that the mammalian septin field adopt a common nomenclature system, based on that adopted by the Mouse Genomic Nomenclature Committee and accepted by the Human Genome Organization Gene Nomenclature Committee. The human and mouse septin genes will be named SEPT1-SEPT10 and Sept1-Sept10, respectively. Splice variants will be designated by an underscore followed by a lowercase "v" and a number, e.g., SEFT4_v1.

Original languageEnglish (US)
Pages (from-to)4111-4113
Number of pages3
JournalMolecular biology of the cell
Issue number12
StatePublished - Dec 1 2002

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology


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