Management and survival of meconium ileus: A 30-year review

C. A. Del Pin, C. Czyrko, M. M. Ziegler, T. F. Scanlin, H. C. Bishop

Research output: Contribution to journalReview articlepeer-review

64 Scopus citations


Cystic fibrosis patients born with meconium ileus (MI) have had an improved outcome over the last three decades. The authors reviewed the impact of surgical management and long-term nutritional care on the survival of patients with MI. Of the 59 cases of MI seen from 1959 to 1989, 48 cases were managed operatively using either the Bishop-Koop ileostomy (BK), the Mikulicz ileostomy, primary resection and anastomosis (RA), or ileostomy. Six-month survival of MI has improved from 37% to 100%. Nonoperative cases (n = 11) had 100% long-term survival. The RA survivors required less late operative intervention (20%) as compared with other surgical patients (81%). A comparison of serial growth percentiles of CF patients with MI with those of their non-MI CF peers showed similar long-term decreases. These data confirm: (1) There is an improved survival for MI independent of the surgical procedure; (2) The BK ileostomy is an effective and time-tested MI treatment; (3) Primary resection and anastomosis in selected cases may have a lower surgical morbidity rate; and (4) Meconium ileus does not adversely affect the long-term nutritional outcome of CF patients.

Original languageEnglish (US)
Pages (from-to)179-185
Number of pages7
JournalAnnals of surgery
Issue number2
StatePublished - 1992
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery


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